{"id":9201,"date":"2023-07-26T08:38:17","date_gmt":"2023-07-26T00:38:17","guid":{"rendered":"http:\/\/zhonghua.gshlw.com\/?p=9201"},"modified":"2023-07-26T08:38:17","modified_gmt":"2023-07-26T00:38:17","slug":"asc22%e8%81%94%e5%90%88%e8%a5%bf%e8%be%be%e6%9c%ac%e8%83%ba%e6%b2%bb%e7%96%97hiv%e4%b8%b4%e5%ba%8a%e7%bb%93%e6%9e%9c%e5%9c%a8%e5%9b%bd%e9%99%85%e8%89%be%e6%bb%8b%e7%97%85%e5%8d%8f%e4%bc%9ahiv%e4%bc%9a","status":"publish","type":"post","link":"http:\/\/zhonghua.gshlw.com\/zixun\/9201.html","title":{"rendered":"ASC22\u8054\u5408\u897f\u8fbe\u672c\u80fa\u6cbb\u7597HIV\u4e34\u5e8a\u7ed3\u679c\u5728\u56fd\u9645\u827e\u6ecb\u75c5\u534f\u4f1aHIV\u4f1a\u8bae\u516c\u5e03"},"content":{"rendered":"
\u6b4c\u793c\u5236\u836f\u6709\u9650\u516c\u53f8\uff08\u9999\u6e2f\u8054\u4ea4\u6240\u4ee3\u7801\uff1a1672\uff0c”\u6b4c\u793c”\uff09\u4eca\u65e5\u5ba3\u5e03\u4e0a\u6d77\u5e02\u516c\u5171\u536b\u751f\u4e34\u5e8a\u4e2d\u5fc3\u5728\u6fb3\u5927\u5229\u4e9a\u5e03\u91cc\u65af\u73ed\u53ca\u7ebf\u4e0a\u4e3e\u884c\u7684\u7b2c12\u5c4a\u56fd\u9645\u827e\u6ecb\u75c5\u534f\u4f1aHIV\u79d1\u5b66\u4f1a\u8bae\u4e0a\u516c\u5e03ASC22\uff08\u6069\u6c83\u5229\u5355\u6297\uff09\u8054\u5408\u897f\u8fbe\u672c\u80fa\u7528\u4e8e\u4eba\u7c7b\u514d\u75ab\u7f3a\u9677\u75c5\u6bd2\uff08HIV\uff09\u611f\u67d3\u529f\u80fd\u6027\u6cbb\u6108\u7684\u4e34\u5e8a\u7ed3\u679c\u3002<\/p>\n
\u8fd9\u9879\u7814\u7a76\u8005\u53d1\u8d77\u7684II\u671f\u8bd5\u9a8c\uff08ClinicalTrials.gov\uff1aNCT05129189\uff09\u7531\u4e0a\u6d77\u5e02\u516c\u5171\u536b\u751f\u4e34\u5e8a\u4e2d\u5fc3\u611f\u67d3\u4e0e\u514d\u75ab\u79d1\u526f\u4e3b\u4efb\u533b\u5e08\u9648\u519b\u535a\u58eb\u9886\u5bfc\uff0c\u5171\u5165\u7ec4\u4e8615\u540d\u5df2\u5b9e\u73b0\u75c5\u6bd2\u5b66\u6291\u5236\u7684HIV\u611f\u67d3\u8005\u3002\u5728\u4e3a\u671f12\u5468\u7684\u6cbb\u7597\u4e2d\uff0c\u53d7\u8bd5\u8005\u6bcf4\u5468\u8fdb\u884c\u76ae\u4e0b\u6ce8\u5c04\u4e00\u6b21ASC22 \uff081\u6beb\u514b\/\u5343\u514b\uff09\uff0c\u5e76\u8054\u5408\u6bcf\u5468\u4e24\u6b21\u53e3\u670d10\u6beb\u514b\u897f\u8fbe\u672c\u80fa\uff0c\u540c\u65f6\u7ef4\u6301\u6297\u9006\u8f6c\u5f55\u75c5\u6bd2\u6cbb\u7597\uff08ART\uff09\u3002\u53d7\u8bd5\u8005\u63a5\u53d724\u5468\u968f\u8bbf\uff0c\u5e76\u68c0\u6d4b\u7ec6\u80de\u76f8\u5173HIV RNA\u3001\u8840\u6d46HIV RNA\u3001\u603bHIV DNA\u548c\u6574\u5408HIV DNA\u4ee5\u53caHIV\u7279\u5f02\u6027CD8+ T\u7ec6\u80de\u529f\u80fd\u6c34\u5e73\u53d8\u5316\u3002<\/p>\n
\u8be5\u7814\u7a76\u65e8\u5728\u8bc4\u4f30ASC22\uff08\u6069\u6c83\u5229\u5355\u6297\uff09\u8054\u5408\u897f\u8fbe\u672c\u80fa\u5728HIV\u611f\u67d3\u8005\u4e2d\u5bf9\u88ab\u611f\u67d3\u7684\u6f5c\u4f0f\u671f\u7ec6\u80de\u75c5\u6bd2\u50a8\u5b58\u5e93\u7684\u7597\u6548\u3002\u6b4c\u793c\u751f\u7269\u79d1\u6280\uff08\u676d\u5dde\uff09\u6709\u9650\u516c\u53f8\uff08\u6b4c\u793c\u5168\u8d44\u5b50\u516c\u53f8\uff09\u63d0\u4f9b\u672c\u6b21\u4e34\u5e8a\u8bd5\u9a8c\u7684ASC22\uff08\u6069\u6c83\u5229\u5355\u6297\uff09\u3002<\/p>\n
\u6b64\u9879II\u671f\u4e34\u5e8a\u8bd5\u9a8c\u663e\u793aASC22\u8054\u5408\u897f\u8fbe\u672c\u80fa\u7597\u6cd5\u5177\u6709\u826f\u597d\u7684\u8010\u53d7\u6027\uff0c\u4e14\u6709\u6548\u5730\u6fc0\u6d3b\u4e86\u6f5c\u4f0f\u7684HIV\u75c5\u6bd2\u5e93\u3002\u53d7\u8bd5\u8005\u7b2c8\u5468\u548c\u7b2c12\u5468\u7684\u7ec6\u80de\u76f8\u5173HIV RNA\u4e0e\u57fa\u7ebf\u6c34\u5e73\u76f8\u6bd4\u663e\u8457\u589e\u52a0\uff0c\u5e73\u5747\u589e\u5e45\u5206\u522b\u4e3a4.27\u500d\u548c3.41\u500d\uff08P=0.001, P=0.006\uff09\u3002HIV \u7ec6\u80de\u76f8\u5173 RNA\u4e0e\u603bDNA\u7684\u6bd4\u503c\u4e5f\u5448\u73b0\u76f8\u540c\u7684\u8d8b\u52bf\uff08\u5206\u522b\u4e3aP=0.038, P=0.017\uff09\u3002\u8be5\u7597\u6cd5\u9700\u5c55\u5f00\u8fdb\u4e00\u6b65\u7814\u7a76\u3002<\/p>\n
\u636e\u4f30\u8ba1\uff0c2022\u5e74\u5168\u7403\u7ea6\u67093,900\u4e07HIV\u611f\u67d3\u8005\uff0c\u7ea6\u670963\u4e07\u4eba\u6b7b\u4e8e\u4e0e\u827e\u6ecb\u75c5\u76f8\u5173\u7684\u75be\u75c5\uff0c\u65b0\u53d1HIV\u611f\u67d3\u8005\u7ea6\u6709130\u4e07[1]\u3002\u8054\u5408ART\u7597\u6cd5\u867d\u7136\u53ef\u6291\u5236\u8840\u6db2\u4e2d\u7684\u75c5\u6bd2\u91cf\uff0c\u4f46\u65e0\u6cd5\u6cbb\u6108HIV\u611f\u67d3\uff0c\u51e0\u4e4e\u6240\u6709HIV\u611f\u67d3\u8005\u5728\u505c\u6b62ART\u6cbb\u7597\u6570\u5468\u6216\u6570\u6708\u5185\u90fd\u4f1a\u51fa\u73b0\u75c5\u6bd2\u53cd\u5f39\u3002<\/p>\n
“\u4e0e\u5065\u5eb7\u53d7\u8bd5\u8005\u76f8\u6bd4\uff0cHIV-1\u578b\u611f\u67d3\u60a3\u8005\u7684PD-1\u548cPD-L1\u8868\u8fbe\u5347\u9ad8\u3002\u8fd1\u671f\u7814\u7a76\u8868\u660e\uff0c\u963b\u65adPD-1\/PD-L1\u901a\u8def\u53ef\u9006\u8f6cHIV\u5728\u60a3\u8005\u4e2d\u7684\u6f5c\u4f0f\u671f\u3002ASC22\u8054\u5408\u897f\u8fbe\u672c\u80fa\u53ef\u6709\u6548\u6fc0\u6d3b\u6f5c\u4f0f\u7684HIV\u75c5\u6bd2\u5e93\uff0c\u8fd9\u4e00\u7ed3\u679c\u4ee4\u4eba\u632f\u594b\u3002”\u6b4c\u793c\u521b\u59cb\u4eba\u3001\u8463\u4e8b\u4f1a\u4e3b\u5e2d\u517c\u9996\u5e2d\u6267\u884c\u5b98\u5434\u52b2\u6893\u535a\u58eb\u8868\u793a\u3002<\/p>\n[1] UNAIDS. Global HIV & AIDS statistics \u2014 FACT SHEET. 2022. https:\/\/www.unaids.org\/en\/resources\/fact-sheet<\/p>\n
\u5173\u4e8e\u56fd\u9645\u827e\u6ecb\u75c5\u534f\u4f1aHIV\u79d1\u5b66\u4f1a\u8bae<\/p>\n
\u56fd\u9645\u827e\u6ecb\u75c5\u534f\u4f1aHIV\u79d1\u5b66\u4f1a\u8bae\u662f\u63a8\u52a8HIV\u9632\u6cbb\u5de5\u4f5c\u7684\u5168\u7403\u9876\u5c16\u5e73\u53f0\u3002\u4f5c\u4e3a\u5168\u7403\u6700\u5927\u7684HIV\u548c\u827e\u6ecb\u75c5\u4f1a\u8bae\uff0c\u79d1\u5b66\u3001\u5ba3\u4f20\u548c\u4eba\u6743\u5728\u8fd9\u91cc\u4ea4\u6c47\uff0c\u8be5\u4f1a\u8bae\u4fc3\u8fdb\u79d1\u5b66\u5bb6\u3001\u653f\u7b56\u5236\u5b9a\u8005\u3001\u533b\u5b66\u4e13\u5bb6\u3001HIV\u611f\u67d3\u8005\u3001\u8d44\u52a9\u8005\u3001\u5a92\u4f53\u548c\u793e\u533a\u7684\u4ea4\u6d41\u5408\u4f5c\u3002\u7b2c12\u5c4a\u56fd\u9645\u827e\u6ecb\u75c5\u534f\u4f1aHIV\u79d1\u5b66\u4f1a\u8bae\uff08IAS 2023\uff09\u4e8e2023\u5e747\u670823\u65e5\u81f326\u65e5\u5728\u6fb3\u5927\u5229\u4e9a\u5e03\u91cc\u65af\u73ed\u53ca\u7ebf\u4e0a\u4e3e\u884c\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"
\u6b4c\u793c\u5236\u836f\u6709\u9650\u516c\u53f8\uff08\u9999\u6e2f\u8054\u4ea4\u6240\u4ee3\u7801\uff1a1672\uff0c”\u6b4c\u793c”\uff09\u4eca\u65e5\u5ba3\u5e03\u4e0a\u6d77\u5e02\u516c\u5171\u536b\u751f\u4e34\u5e8a\u4e2d\u5fc3\u5728\u6fb3\u5927\u5229\u4e9a\u5e03\u91cc\u65af\u73ed\u53ca\u7ebf\u4e0a\u4e3e\u884c\u7684\u7b2c12\u5c4a\u56fd\u9645\u827e\u6ecb\u75c5\u534f\u4f1aHIV\u79d1\u5b66\u4f1a\u8bae\u4e0a\u516c\u5e03ASC22\uff08\u6069\u6c83\u5229\u5355\u6297\uff09\u8054\u5408\u897f\u8fbe\u672c\u80fa\u7528\u4e8e\u4eba\u7c7b\u514d\u75ab\u7f3a\u9677\u75c5\u6bd2\uff08H […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2],"tags":[],"_links":{"self":[{"href":"http:\/\/zhonghua.gshlw.com\/wp-json\/wp\/v2\/posts\/9201"}],"collection":[{"href":"http:\/\/zhonghua.gshlw.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/zhonghua.gshlw.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/zhonghua.gshlw.com\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/zhonghua.gshlw.com\/wp-json\/wp\/v2\/comments?post=9201"}],"version-history":[{"count":2,"href":"http:\/\/zhonghua.gshlw.com\/wp-json\/wp\/v2\/posts\/9201\/revisions"}],"predecessor-version":[{"id":9208,"href":"http:\/\/zhonghua.gshlw.com\/wp-json\/wp\/v2\/posts\/9201\/revisions\/9208"}],"wp:attachment":[{"href":"http:\/\/zhonghua.gshlw.com\/wp-json\/wp\/v2\/media?parent=9201"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/zhonghua.gshlw.com\/wp-json\/wp\/v2\/categories?post=9201"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/zhonghua.gshlw.com\/wp-json\/wp\/v2\/tags?post=9201"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}